Ser1164
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Home > Phosphorylation Site Page: > Ser1164  -  BRCA1 (human)

Site Information
GEIKEDTsFAENDIk   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 36135579

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
PLK1 (human) ( 1 )
Kinases, in vitro:
PLK1 (human) ( 1 )
Treatments:
BI2536 ( 1 )

Downstream Regulation
Effects of modification on BRCA1:
intracellular localization ( 1 )
Effects of modification on biological processes:
DNA repair, induced ( 1 )

References 

1

Chabalier-Taste C, et al. (2016) Polo-like kinase 1 mediates BRCA1 phosphorylation and recruitment at DNA double-strand breaks. Oncotarget 7, 2269-83
26745677   Curated Info

2

Sharma K, et al. (2014) Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling. Cell Rep 8, 1583-94
25159151   Curated Info

3

Beli P, et al. (2012) Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response. Mol Cell 46, 212-25
22424773   Curated Info