Tyr1022
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Home > Phosphorylation Site Page: > Tyr1022  -  HER4 (human)

Site Information
DMMDAEEyLVPQAFN   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 36100601

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
COS7 (fibroblast) ( 1 )

Downstream Regulation
Effects of modification on HER4:
molecular association, regulation ( 1 , 2 )
Effects of modification on biological processes:
cell motility, induced ( 1 )
Induce interaction with:
CRK (human) ( 2 ) , CSK (human) ( 2 ) , VAV3 (human) ( 1 )

References 

1

Ojala VK, et al. (2020) The guanine nucleotide exchange factor VAV3 participates in ERBB4-mediated cancer cell migration. J Biol Chem 295
32561640   Curated Info

2

Schulze WX, Deng L, Mann M (2005) Phosphotyrosine interactome of the ErbB-receptor kinase family. Mol Syst Biol 1, 2005.0008
16729043   Curated Info

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