Ser71
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Home > Phosphorylation Site Page: > Ser71  -  ARHGEF7 (rat)

Site Information
KPSEkPVsPKSGTLK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3573357

In vivo Characterization
Methods used to characterize site in vivo:
[32P] ATP in vitro ( 1 ) , mass spectrometry ( 2 ) , mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
'brain, brainstem' ( 2 ) , 'brain, cerebellum' ( 2 ) , 'brain, cerebral cortex' ( 2 ) , 293 (epithelial) ( 1 ) , lung ( 2 ) , mpkCCD (renal) ( 1 ) , testis ( 2 )

Upstream Regulation
Putative in vivo kinases:
AMPKA1 (human) ( 1 )
Kinases, in vitro:
AMPKA1 (human) ( 1 )
Treatments:
A-769662 ( 1 ) , acadesine ( 1 )

Downstream Regulation
Effects of modification on ARHGEF7:
molecular association, regulation ( 1 ) , protein conformation ( 1 )
Induce interaction with:
14-3-3 beta (human) ( 1 ) , NEDD4 iso2 (human) ( 1 )

References 

1

Ho PY, et al. (2019) AMPK phosphorylation of the ╬▓Pix exchange factor regulates the assembly and function of an ENaC inhibitory complex in kidney epithelial cells. Am J Physiol Renal Physiol
31566435   Curated Info

2

Lundby A, et al. (2012) Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. Nat Commun 3, 876
22673903   Curated Info