Thr3361

Site Information
yPMVEyCtPTTSGED SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 35542206

In vivo Characterization
Methods used to characterize site in vivo:	immunoassay ( 1 ) , immunoprecipitation ( 1 ) , mass spectrometry ( 1 , 2 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 1 ) , C2C12 (myoblast) ( 1 ) , HeLa (cervical) ( 2 )

Downstream Regulation
Effects of modification on dystrophin:	molecular association, regulation ( 1 ) , protein stabilization ( 1 )
Effects of modification on biological processes:	cytoskeletal reorganization ( 1 )
Induce interaction with:	DAG1 (human) ( 1 )

References
1	Swiderski K, et al. (2014) Phosphorylation within the cysteine-rich region of dystrophin enhances its association with β-dystroglycan and identifies a potential novel therapeutic target for skeletal muscle wasting. Hum Mol Genet 23, 6697-711 25082828 Curated Info
2	Sharma K, et al. (2014) Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling. Cell Rep 8, 1583-94 25159151 Curated Info