Tyr1114
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Home > Phosphorylation Site Page: > Tyr1114  -  JMJD1A (human)

Site Information
ITPEDRKyGTTNLHL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 35527104

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
breast cancer ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
Ack (human) ( 1 )
Treatments:
4-HT ( 1 ) , AIM-100 ( 1 ) , dasatinib ( 1 ) , heregulin ( 1 ) , siRNA ( 1 )

Downstream Regulation
Effects of modification on JMJD1A:
enzymatic activity, inhibited ( 1 )
Effects of modification on biological processes:
transcription, induced ( 1 )

References 

1

Mahajan K, Lawrence HR, Lawrence NJ, Mahajan NP (2014) ACK1 Tyrosine Kinase Interacts with Histone Demethylase KDM3A to Regulate the Mammary Tumor Oncogene HOXA1. J Biol Chem 289, 28179-91
25148682   Curated Info