Ser1791
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Home > Phosphorylation Site Page: > Ser1791  -  Notch 1 (mouse)

Site Information
LkPLKNAsDGALMDD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 35502500

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , microscopy-colocalization with upstream kinase ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
PKCZ (human) ( 1 )
Kinases, in vitro:
PKCZ (human) ( 1 )

Downstream Regulation
Effects of modification on Notch 1:
intracellular localization ( 1 )
Effects of modification on biological processes:
cell differentiation, inhibited ( 1 ) , transcription, induced ( 1 )

References 

1

Sjöqvist M, et al. (2014) PKCζ regulates Notch receptor routing and activity in a Notch signaling-dependent manner. Cell Res 24, 433-50
24662486   Curated Info