Thr4338
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.7.4
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Thr4338  -  RYR1 (mouse)

Site Information
ALLWALVtRAGGAGA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 34348504

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 , 2 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
neuroblastoma ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Regulatory protein:
OGT (human) ( 1 )
Putative in vivo kinases:
NEK10 (human) ( 1 )
Treatments:
siRNA ( 1 )

Downstream Regulation
Effects of modification on RYR1:
protein degradation ( 1 ) , ubiquitination ( 1 )

References 

1

Yan W, et al. (2022) Cancer-cell-secreted miR-122 suppresses O-GlcNAcylation to promote skeletal muscle proteolysis. Nat Cell Biol
35469018   Curated Info

2

Wang Y, et al. (2011) Spatial phosphoprotein profiling reveals a compartmentalized extracellular signal-regulated kinase switch governing neurite growth and retraction. J Biol Chem 286, 18190-201
21454597   Curated Info