Tyr1169
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Home > Phosphorylation Site Page: > Tyr1169  -  VEGFR1 (human)

Site Information
VQQDGKDyIPINAIL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448208

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , phosphoamino acid analysis ( 1 ) , phosphopeptide mapping ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
VEGFR1 (human) ( 1 )
Kinases, in vitro:
VEGFR1 (human) ( 1 )
Treatments:
VEGF ( 1 )

Downstream Regulation
Effects of modification on VEGFR1:
molecular association, regulation ( 1 )
Induce interaction with:
PLCG1 (mouse) ( 1 )

References 

1

Sawano A, Takahashi T, Yamaguchi S, Shibuya M (1997) The phosphorylated 1169-tyrosine containing region of flt-1 kinase (VEGFR-1) is a major binding site for PLCgamma. Biochem Biophys Res Commun 238, 487-91
9299537   Curated Info