Thr7
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Home > Phosphorylation Site Page: > Thr7  -  RAB5A (human)

Site Information
_MAsrGAtRPNGPNT   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 33622402

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
lymphoma ( 1 ) , T cell lymphoma ( 1 )
Relevant cell line - cell type - tissue:
HUT-78 (T lymphocyte) ( 1 ) , T lymphocyte-blood ( 1 )

Upstream Regulation
Putative in vivo kinases:
PKCE (human) ( 1 )
Treatments:
bisindolylmaleimide ( 1 ) , CXCL12 ( 1 ) , ICAM-1 ( 1 ) , phorbol_ester ( 1 )

Downstream Regulation
Effects of modification on RAB5A:
intracellular localization ( 1 )
Effects of modification on biological processes:
cell motility, induced ( 1 ) , cytoskeletal reorganization ( 1 )

References 

1

Ong ST, et al. (2014) Phosphorylation of Rab5a protein by protein kinase Cϵ is crucial for T-cell migration. J Biol Chem 289, 19420-34
24872409   Curated Info