Ser649

Site Information
AMRRRRssDPLGDTA SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 3204399

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 2 , 3 , 4 )
Relevant cell line - cell type - tissue:	'fat, brown' ( 4 ) , brain ( 4 ) , kidney ( 4 ) , liver ( 2 , 4 ) , lung ( 4 ) , MEF (fibroblast) [TSC2 (mouse), homozygous knockout] ( 3 ) , MEF (fibroblast) ( 3 ) , spleen ( 4 )

References
1	Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704 24719451 Curated Info
2	Wilson-Grady JT, Haas W, Gygi SP (2013) Quantitative comparison of the fasted and re-fed mouse liver phosphoproteomes using lower pH reductive dimethylation. Methods 61, 277-86 23567750 Curated Info
3	Yu Y, et al. (2011) Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. Science 332, 1322-6 21659605 Curated Info
4	Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89 21183079 Curated Info