Lys605

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Home > Succinylation Site Page: > Lys605 - ACO2 (mouse)

Site Information
SAAGPWLkFRGHLDN SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 33405046

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 )
Relevant cell line - cell type - tissue:	liver ( 1 , 2 )

Upstream Regulation
Regulatory protein:	SIRT5 (mouse) ( 2 )
Treatments:	glucose ( 1 ) , high-fat diet ( 1 )

References
1	Meyer JG, et al. (2018) Temporal dynamics of liver mitochondrial protein acetylation and succinylation and metabolites due to high fat diet and/or excess glucose or fructose. PLoS One 30586434 Curated Info
2	Rardin MJ, et al. (2013) SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks. Cell Metab 18, 920-33 24315375 Curated Info

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