Ser246
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Home > Phosphorylation Site Page: > Ser246  -  HePTP (human)

Site Information
QYQEERRsVkHILFS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 460715

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 )
Relevant cell line - cell type - tissue:
T lymphocyte-blood ( 1 )

Upstream Regulation
Kinases, in vitro:
PKCT (human) ( 1 )
Treatments:
anti-CD28 ( 1 ) , phorbol_ester ( 1 ) , rottlerin ( 1 )

Downstream Regulation
Effects of modification on HePTP:
enzymatic activity, induced ( 1 ) , intracellular localization ( 1 )

References 

1

Nika K, et al. (2006) Lipid raft targeting of hematopoietic protein tyrosine phosphatase by protein kinase C theta-mediated phosphorylation. Mol Cell Biol 26, 1806-16
16479000   Curated Info