Lys311
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Home > Succinylation Site Page: > Lys311  -  PKM (human)

Site Information
EkVFLAQkMMIGRCN   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 33357166

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 )
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 2 )

Downstream Regulation
Effects of modification on PKM:
enzymatic activity, induced ( 1 ) , protein conformation ( 1 )

References 

1

Wang F, et al. (2017) SIRT5 Desuccinylates and Activates Pyruvate Kinase M2 to Block Macrophage IL-1β Production and to Prevent DSS-Induced Colitis in Mice. Cell Rep 19, 2331-2344
28614718   Curated Info

2

Weinert BT, et al. (2013) Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation. Cell Rep 4, 842-51
23954790   Curated Info

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