Thr102

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Home > Phosphorylation Site Page: > Thr102 - NUMB (human)

Site Information
LRVVDEKtKDLIVDQ SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 3333403

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:	HeLa (cervical) ( 1 )

Upstream Regulation
Putative in vivo kinases:	AAK1 (human) ( 1 )
Kinases, in vitro:	AAK1 (human) ( 1 )

Downstream Regulation
Effects of modification on NUMB:	activity, induced ( 1 ) , intracellular localization ( 1 )
Effects of modification on biological processes:	endocytosis, altered ( 1 )

References
1	Sorensen EB, Conner SD (2008) AAK1 regulates Numb function at an early step in clathrin-mediated endocytosis. Traffic 9, 1791-800 18657069 Curated Info

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