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Site Information |
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DWVFINytyKRFEGL SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 460659 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Disease tissue studied: | |
Relevant cell line - cell type - tissue: |
Upstream Regulation | |
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Regulatory protein: | |
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Kinases, in vitro: | |
Treatments: |
Downstream Regulation | |
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Effects of modification on NDR1: | |
Effects of modification on biological processes: | |
Induce interaction with: |
References | |
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Enomoto A, et al. (2019) Prevention of calpain-dependent degradation of STK38 by MEKK2-mediated phosphorylation. Sci Rep 9, 16010
31690749 Curated Info |
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Yan M, et al. (2015) Regulation of NDR1 activity by PLK1 ensures proper spindle orientation in mitosis. Sci Rep 5, 10449
26057687 Curated Info |
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Du Z, Tong X, Ye X (2013) Cyclin D1 promotes cell cycle progression through enhancing NDR1/2 kinase activity independent of cyclin-dependent kinase 4. J Biol Chem 288, 26678-87
23897809 Curated Info |
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Stokes MP, et al. (2012) PTMScan Direct: Identification and Quantification of Peptides from Critical Signaling Proteins by Immunoaffinity Enrichment Coupled with LC-MS/MS. Mol Cell Proteomics 11, 187-201
22322096 Curated Info |
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Ultanir SK, et al. (2012) Chemical Genetic Identification of NDR1/2 Kinase Substrates AAK1 and Rabin8 Uncovers Their Roles in Dendrite Arborization and Spine Development. Neuron 73, 1127-42
22445341 Curated Info |
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Mulhern D (2012) CST Curation Set: 13830; Year: 2012; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: (K/R)XpSX(K/R)
Curated Info |
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Hergovich A, et al. (2009) The MST1 and hMOB1 tumor suppressors control human centrosome duplication by regulating NDR kinase phosphorylation. Curr Biol 19, 1692-702
19836237 Curated Info |
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Tamaskovic R, et al. (2003) Mechanism of Ca2+-mediated regulation of NDR protein kinase through autophosphorylation and phosphorylation by an upstream kinase. J Biol Chem 278, 6710-8
12493777 Curated Info |