Ser246
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Home > Phosphorylation Site Page: > Ser246  -  Akt1 (human)

Site Information
LSRERVFsEDRARFY   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 460649

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 )
Relevant cell line - cell type - tissue:
MCF-7 (breast cell) ( 1 )

Upstream Regulation
Kinases, in vitro:
Akt1 (human) ( 1 )

Downstream Regulation
Effects of modification on Akt1:
enzymatic activity, induced ( 1 )
Effects of modification on biological processes:
apoptosis, inhibited ( 1 )

References 

1

Li X, et al. (2006) Autophosphorylation of Akt at threonine 72 and serine 246. A potential mechanism of regulation of Akt kinase activity. J Biol Chem 281, 13837-43
16549426   Curated Info

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