Thr455
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Home > Phosphorylation Site Page: > Thr455  -  ARAF (human)

Site Information
FGLAtVktRWsGAQP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3306307

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 )
Disease tissue studied:
lung cancer ( 2 ) , non-small cell lung cancer ( 2 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 1 ) , lung ( 2 )

Downstream Regulation
Effects of modification on ARAF:
enzymatic activity, induced ( 1 )

References 

1

Baljuls A, et al. (2008) Positive regulation of A-RAF by phosphorylation of isoform-specific hinge segment and identification of novel phosphorylation sites. J Biol Chem 283, 27239-54
18662992   Curated Info

2

Rikova K (2008) CST Curation Set: 4039; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info