Ser439
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Home > Phosphorylation Site Page: > Ser439  -  CACNA1C (rabbit)

Site Information
GVLSGEFsKEREKAK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 460571

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
CAMK2A (human) ( 2 )

References 

1

Yarotskyy V, Gao G, Peterson BZ, Elmslie KS (2009) The Timothy syndrome mutation of cardiac CaV1.2 (L-type) channels: multiple altered gating mechanisms and pharmacological restoration of inactivation. J Physiol 587, 551-65
19074970   Curated Info

2

Erxleben C, et al. (2006) Cyclosporin and Timothy syndrome increase mode 2 gating of CaV1.2 calcium channels through aberrant phosphorylation of S6 helices. Proc Natl Acad Sci U S A 103, 3932-7
16537462   Curated Info