Lys265
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Home > Sumoylation Site Page: > Lys265  -  Fos (mouse)

Site Information
SISNVELkAEPFDDF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3289000

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , modification-specific antibody ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on Fos:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, inhibited ( 1 )
Inhibit interaction with:
DNA ( 1 )

References 

1

Tempé D, et al. (2014) SUMOylation of the inducible (c-Fos:c-Jun)/AP-1 transcription complex occurs on target promoters to limit transcriptional activation. Oncogene 33, 921-7
23396363   Curated Info