Thr189
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Home > Phosphorylation Site Page: > Thr189  -  LKB1 (human)

Site Information
LLLtTGGtLKISDLG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448149

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 2 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HT1080 (fibroblast) ( 2 ) , platelet-blood ( 1 )

Upstream Regulation
Kinases, in vitro:
LKB1 (human) ( 2 )
Treatments:
calyculin_A ( 1 )

Downstream Regulation
Effects of modification on biological processes:
apoptosis, inhibited ( 2 )

References 

1

Lerea KM, Venjara AY, Olson SC, Kelly MR (2007) Threonine phosphorylation of integrin beta3 in calyculin A-treated platelets is selectively sensitive to 5'-iodotubercidin. Biochim Biophys Acta 1773, 185-91
17052767   Curated Info

2

Karuman P, et al. (2001) The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death. Mol Cell 7, 1307-19
11430832   Curated Info