Ser50

Site Information
SRRRHNssDGFFNNG SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 3246167

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 , 5 )
Disease tissue studied:	lung cancer ( 1 ) , non-small cell lung cancer ( 1 )
Relevant cell line - cell type - tissue:	Calu 6 (pulmonary) ( 1 ) , H2009 (pulmonary) ( 1 ) , H2077 (pulmonary) ( 1 ) , H2887 (pulmonary) ( 1 ) , H322M (pulmonary) ( 1 ) , HCC1359 (pulmonary) ( 1 ) , HCC2279 (pulmonary) ( 1 ) , HCC4006 (pulmonary) ( 1 ) , HOP62 (pulmonary) ( 1 ) , Jurkat (T lymphocyte) ( 3 , 4 ) , NCI-H1395 (pulmonary) ( 1 ) , NCI-H157 (pulmonary) ( 1 ) , NCI-H1648 (pulmonary) ( 1 ) , NCI-H1666 (pulmonary) ( 1 ) , NCI-H2030 (pulmonary) ( 1 ) , NCI-H2172 (pulmonary) ( 1 ) , NCI-H322 (pulmonary) ( 1 ) , NCI-H3255 (pulmonary) ( 5 )

References
1	Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68 22617229 Curated Info
2	Rikova K (2012) CST Curation Set: 14275; Year: 2012; Biosample/Treatment: cell line, Tumor pilot study 2mg/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS/T) Immunoaffinity Beads Cat#: 1978 Curated Info
3	Moritz A (2009) CST Curation Set: 8726; Year: 2009; Biosample/Treatment: cell line, Jurkat/calyculin_A; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS/T) Immunoaffinity Beads Cat#: 1978 Curated Info
4	Possemato A (2009) CST Curation Set: 8595; Year: 2009; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Curated Info
5	Possemato A (2009) CST Curation Set: 7424; Year: 2009; Biosample/Treatment: cell line, NCI-H3255/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS/T) Immunoaffinity Beads Cat#: 1978 Curated Info