Tyr567
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Home > Phosphorylation Site Page: > Tyr567  -  CTPS (mouse)

Site Information
RLsPRDtysDRsGss   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3181151

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 )
Relevant cell line - cell type - tissue:
MEF (fibroblast) ( 1 ) , MEF (fibroblast) [Raptor (mouse), knockdown] ( 1 ) , MEF (fibroblast) [RICTOR (mouse), knockdown] ( 1 ) , MEF (fibroblast) [TSC2 (mouse), homozygous knockout] ( 2 ) , P19 (testicular) ( 3 )

Upstream Regulation
Regulatory protein:
Raptor (mouse) ( 1 ) , RICTOR (mouse) ( 1 )

References 

1

Robitaille AM, et al. (2013) Quantitative phosphoproteomics reveal mTORC1 activates de novo pyrimidine synthesis. Science 339, 1320-3
23429704   Curated Info

2

Yu Y, et al. (2011) Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. Science 332, 1322-6
21659605   Curated Info

3

Smith JC, et al. (2007) A differential phosphoproteomic analysis of retinoic acid-treated P19 cells. J Proteome Res 6, 3174-86
17622165   Curated Info