Tyr175

Site Information
REEVGAGyNsEDEYE SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 3209025

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 )
Relevant cell line - cell type - tissue:	32Dcl3 (myeloid) [FLT3 (mouse), transfection, chimera with human FLT3-ITD mutant (corresponding to wild type P36888 ( 2 ) , 32Dcl3 (myeloid) ( 2 ) , brain ( 1 ) , kidney ( 1 ) , liver ( 1 ) , lung ( 1 ) , pancreas ( 1 ) , spleen ( 1 ) , testis ( 1 )

Upstream Regulation
Regulatory protein:	FLT3 (mouse) ( 2 )

References
1	Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89 21183079 Curated Info
2	Choudhary C, et al. (2009) Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes. Mol Cell 36, 326-39 19854140 Curated Info