Ser467
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Home > Phosphorylation Site Page: > Ser467  -  KLC3 (mouse)

Site Information
AGMKRAMsLNMLNVD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3202797

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 )
Disease tissue studied:
neuroblastoma ( 6 ) , melanoma skin cancer ( 9 )
Relevant cell line - cell type - tissue:
'fat, brown' ( 7 ) , brain ( 7 ) , kidney ( 7 ) , lung ( 7 ) , macrophage-peritoneum ( 4 ) , MEF (fibroblast) [TSC2 (mouse), homozygous knockout] ( 5 ) , mpkCCD (renal) ( 8 ) , N1E-115 (neuron) ( 6 ) , pancreas ( 7 ) , RAW 264.7 (macrophage) ( 2 ) , skin [mGluR1 (mouse), transgenic, TG mutant mice] ( 9 ) , spleen ( 7 ) , stromal ( 3 )

Upstream Regulation
Regulatory protein:
MPRIP (mouse) ( 4 )
Treatments:
LPA ( 6 )

References 

1

Sacco F, et al. (2016) Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion. Nat Commun 7, 13250
27841257   Curated Info

2

Pinto SM, et al. (2015) Quantitative phosphoproteomic analysis of IL-33-mediated signaling. Proteomics 15, 532-44
25367039   Curated Info

3

Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704
24719451   Curated Info

4

Wu X, et al. (2012) Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics. Mol Cell Proteomics 11, 1640-51
22942356   Curated Info

5

Yu Y, et al. (2011) Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. Science 332, 1322-6
21659605   Curated Info

6

Wang Y, et al. (2011) Spatial phosphoprotein profiling reveals a compartmentalized extracellular signal-regulated kinase switch governing neurite growth and retraction. J Biol Chem 286, 18190-201
21454597   Curated Info

7

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

8

Rinschen MM, et al. (2010) Quantitative phosphoproteomic analysis reveals vasopressin V2-receptor-dependent signaling pathways in renal collecting duct cells. Proc Natl Acad Sci U S A 107, 3882-7
20139300   Curated Info

9

Zanivan S, et al. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res 7, 5314-26
19367708   Curated Info