Ser508
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Home > Phosphorylation Site Page: > Ser508  -  TSC1 (mouse)

Site Information
DsPFyRDsLsGsQRK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3208191

In vivo Characterization
Methods used to characterize site in vivo:
phospho-antibody ( 2 ) , western blotting ( 2 )
Disease tissue studied:
breast cancer ( 2 ) , diabetes mellitus ( 2 ) , type 2 diabetes ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
high-fat diet ( 2 )

References 

1

Schröfelbauer B, et al. (2012) NEMO Ensures Signaling Specificity of the Pleiotropic IKKβ by Directing Its Kinase Activity toward IκBα. Mol Cell 47, 111-21
22633953   Curated Info

2

Lee DF, et al. (2008) IKKbeta suppression of TSC1 function links the mTOR pathway with insulin resistance. Int J Mol Med 22, 633-8
18949383   Curated Info