Ser149
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Home > Phosphorylation Site Page: > Ser149  -  MgcRacGAP (human)

Site Information
RLstIDEsGsILsDI   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3211986

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 ) , mutation of modification site ( 1 )
Disease tissue studied:
hepatocellular carcinoma ( 1 )
Relevant cell line - cell type - tissue:
HCCLM3 (hepatic) ( 1 ) , HeLa (cervical) ( 2 )

Upstream Regulation
Putative in vivo kinases:
PLK1 (human) ( 1 )

Downstream Regulation
Effects of modification on MgcRacGAP:
enzymatic activity, induced ( 1 )
Effects of modification on biological processes:
cell cycle regulation ( 1 )

References 

1

Chen J, et al. (2022) Targeting anillin inhibits tumorigenesis and tumor growth in hepatocellular carcinoma via impairing cytokinesis fidelity. Oncogene 41, 3118-3130
35477750   Curated Info

2

Dephoure N, et al. (2008) A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A 105, 10762-7
18669648   Curated Info

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