Ser400

Site Information
SVAAPEKsssNDsVD SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 3210315

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 )
Disease tissue studied:	lung cancer ( 1 ) , non-small cell lung cancer ( 1 )
Relevant cell line - cell type - tissue:	Calu 6 (pulmonary) ( 1 ) , H2077 (pulmonary) ( 1 ) , H322M (pulmonary) ( 1 ) , HCC366 (pulmonary) ( 1 ) , HCC78 (pulmonary) ( 1 ) , HeLa (cervical) ( 3 , 4 ) , HUES-9 ('stem, embryonic') ( 2 ) , LOU-NH91 (squamous) ( 1 ) , NCI-H1395 (pulmonary) ( 1 ) , NCI-H1648 (pulmonary) ( 1 ) , NCI-H2030 (pulmonary) ( 1 ) , NCI-H460 (pulmonary) ( 1 )

References
1	Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68 22617229 Curated Info
2	Rigbolt KT, et al. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. Sci Signal 4, rs3 21406692 Curated Info
3	Dephoure N, et al. (2008) A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A 105, 10762-7 18669648 Curated Info
4	Ruse CI, et al. (2008) Motif-specific sampling of phosphoproteomes. J Proteome Res 7, 2140-50 18452278 Curated Info