Ser54
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Home > Phosphorylation Site Page: > Ser54  -  Snail2 (human)

Site Information
ILSSGAYsPITVWTT   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 31961400

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
bone cancer ( 1 ) , lung cancer ( 1 )
Relevant cell line - cell type - tissue:
CL1-5 (pulmonary) ( 1 ) , U2OS (bone cell) ( 1 )

Upstream Regulation
Putative in vivo kinases:
CDK2 (human) ( 1 )
Kinases, in vitro:
CDK2 (human) ( 1 )
Treatments:
CHEMBL267048 ( 1 ) , siRNA ( 1 ) , thymidine ( 1 )

Downstream Regulation
Effects of modification on Snail2:
protein degradation ( 1 ) , ubiquitination ( 1 )
Effects of modification on biological processes:
cell cycle regulation ( 1 )

References 

1

Wang WL, et al. (2015) Slug is temporally regulated by cyclin E in cell cycle and controls genome stability. Oncogene 34, 1116-25
24662826   Curated Info

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