Lys445
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.8.2
Powered by Cell Signaling Technology
Home > Sumoylation Site Page: > Lys445  -  FOXM1 iso2 (human)

Site Information
LLPVQTIkEEEIQPG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 31898501

In vivo Characterization
Methods used to characterize site in vivo:
immunoassay ( 1 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
bone cancer ( 1 )
Relevant cell line - cell type - tissue:
U2OS (bone cell) ( 1 )

Upstream Regulation
Regulatory protein:
PLK1 (human) ( 1 )

Downstream Regulation
Effects of modification on FOXM1 iso2:
protein degradation ( 1 )
Effects of modification on biological processes:
transcription, inhibited ( 1 )

References 

1

Zhang J, et al. (2015) Polo-like Kinase 1-mediated Phosphorylation of Forkhead Box Protein M1b Antagonizes Its SUMOylation and Facilitates Its Mitotic Function. J Biol Chem 290, 3708-19
25533473   Curated Info

PhosphoSitePlus® is a registered trademark of Cell Signaling Technology.
Use of PSP data is subject to a formal license agreement. Learn more

©2003-2025 Cell Signaling Technology, Inc.