Lys201
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Home > Sumoylation Site Page: > Lys201  -  FOXM1 iso2 (human)

Site Information
GLGSRSIkQEMEEKE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 31898500

In vivo Characterization
Methods used to characterize site in vivo:
immunoassay ( 1 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
bone cancer ( 1 )
Relevant cell line - cell type - tissue:
U2OS (bone cell) ( 1 )

Upstream Regulation
Regulatory protein:
PLK1 (human) ( 1 )

Downstream Regulation
Effects of modification on FOXM1 iso2:
protein degradation ( 1 )
Effects of modification on biological processes:
transcription, inhibited ( 1 )

References 

1

Zhang J, et al. (2015) Polo-like Kinase 1-mediated Phosphorylation of Forkhead Box Protein M1b Antagonizes Its SUMOylation and Facilitates Its Mitotic Function. J Biol Chem 290, 3708-19
25533473   Curated Info

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