Ser437

Site Information
LKLIssDsED_____ SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 3192040

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 4 , 5 )
Disease tissue studied:	leukemia ( 4 ) , acute myelogenous leukemia ( 4 ) , lung cancer ( 1 ) , non-small cell lung cancer ( 1 )
Relevant cell line - cell type - tissue:	Flp-In T-Rex-293 (epithelial) [PRKD1 (human), genetic knockin] ( 2 ) , H2009 (pulmonary) ( 1 ) , H2077 (pulmonary) ( 1 ) , H2887 (pulmonary) ( 1 ) , H322M (pulmonary) ( 1 ) , HCC366 (pulmonary) ( 1 ) , HCC78 (pulmonary) ( 1 ) , HeLa (cervical) ( 5 ) , HOP62 (pulmonary) ( 1 ) , KG-1 (myeloid) ( 4 ) , LOU-NH91 (squamous) ( 1 ) , NCI-H1395 (pulmonary) ( 1 ) , NCI-H1568 (pulmonary) ( 1 ) , NCI-H2030 (pulmonary) ( 1 ) , NCI-H322 (pulmonary) ( 1 ) , NCI-H460 (pulmonary) ( 1 ) , NCI-H520 (squamous) ( 1 ) , NCI-H647 (pulmonary) ( 1 ) , PC9 (pulmonary) ( 1 )

References
1	Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68 22617229 Curated Info
2	Franz-Wachtel M, et al. (2012) Global detection of protein kinase D-dependent phosphorylation events in nocodazole-treated human cells. Mol Cell Proteomics 11, 160-70 22496350 Curated Info
3	Beli P, et al. (2012) Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response. Mol Cell 46, 212-25 22424773 Curated Info
4	Weber C, Schreiber TB, Daub H (2012) Dual phosphoproteomics and chemical proteomics analysis of erlotinib and gefitinib interference in acute myeloid leukemia cells. J Proteomics 75, 1343-56 22115753 Curated Info
5	Dephoure N, et al. (2008) A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A 105, 10762-7 18669648 Curated Info