Ser468
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Home > Phosphorylation Site Page: > Ser468  -  hnRNP M (human)

Site Information
GLDHMAssIERMGQt   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3191710

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 4 , 5 , 6 , 7 , 8 , 9 )
Disease tissue studied:
breast cancer ( 5 ) , cervical cancer ( 8 ) , cervical adenocarcinoma ( 8 ) , leukemia ( 7 ) , acute myelogenous leukemia ( 7 ) , lung cancer ( 2 ) , non-small cell lung adenocarcinoma ( 2 ) , melanoma skin cancer ( 1 )
Relevant cell line - cell type - tissue:
BT-20 (breast cell) ( 5 ) , BT-549 (breast cell) ( 5 ) , Flp-In T-Rex-293 (epithelial) ( 6 ) , Flp-In T-Rex-293 (epithelial) [PRKD1 (human), genetic knockin] ( 6 ) , HeLa (cervical) ( 4 , 9 ) , HeLa S3 (cervical) ( 8 ) , K562 (erythroid) ( 4 ) , KG-1 (myeloid) ( 7 ) , MDA-MB-231 (breast cell) ( 5 ) , MDA-MB-468 (breast cell) ( 5 ) , PC9 (pulmonary) ( 2 ) , WM239A (epidermal) ( 1 )

Upstream Regulation
Treatments:
nocodazole ( 8 )

References 

1

Stuart SA, et al. (2015) A Phosphoproteomic Comparison of B-RAFV600E and MKK1/2 Inhibitors in Melanoma Cells. Mol Cell Proteomics 14, 1599-615
25850435   Curated Info

2

Tsai CF, et al. (2015) Large-scale determination of absolute phosphorylation stoichiometries in human cells by motif-targeting quantitative proteomics. Nat Commun 6, 6622
25814448   Curated Info

3

Shiromizu T, et al. (2013) Identification of missing proteins in the neXtProt database and unregistered phosphopeptides in the PhosphoSitePlus database as part of the Chromosome-centric Human Proteome Project. J Proteome Res 12, 2414-21
23312004   Curated Info

4

Zhou H, et al. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome. J Proteome Res 12, 260-71
23186163   Curated Info

5

Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68
22617229   Curated Info

6

Franz-Wachtel M, et al. (2012) Global detection of protein kinase D-dependent phosphorylation events in nocodazole-treated human cells. Mol Cell Proteomics 11, 160-70
22496350   Curated Info

7

Weber C, Schreiber TB, Daub H (2012) Dual phosphoproteomics and chemical proteomics analysis of erlotinib and gefitinib interference in acute myeloid leukemia cells. J Proteomics 75, 1343-56
22115753   Curated Info

8

Olsen JV, et al. (2010) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Sci Signal 3, ra3
20068231   Curated Info

9

Dephoure N, et al. (2008) A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A 105, 10762-7
18669648   Curated Info