Thr307
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Home > Phosphorylation Site Page: > Thr307  -  PPP1CC (human)

Site Information
EKKkPNAtRPVtPPR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3190033

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 )
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 2 ) , liver ( 1 )

Upstream Regulation
Kinases, in vitro:
NEK2 (human) ( 3 )

Downstream Regulation
Effects of modification on PPP1CC:
enzymatic activity, inhibited ( 3 )

References 

1

Bian Y, et al. (2014) An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. J Proteomics 96, 253-62
24275569   Curated Info

2

Dephoure N, et al. (2008) A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A 105, 10762-7
18669648   Curated Info

3

Helps NR, Luo X, Barker HM, Cohen PT (2000) NIMA-related kinase 2 (Nek2), a cell-cycle-regulated protein kinase localized to centrosomes, is complexed to protein phosphatase 1. Biochem J 349, 509-18
10880350   Curated Info

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