Ser77
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Home > Phosphorylation Site Page: > Ser77  -  RARG (human)

Site Information
SEEMVPSsPsPPPPP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 455543

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 2 ) , mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , phosphopeptide mapping ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 2 ) , MCF-7 (breast cell) ( 1 )

Upstream Regulation
Kinases, in vitro:
CDK7 (human) ( 2 ) , GTF2F1 (human) ( 2 )

Downstream Regulation
Effects of modification on RARG:
activity, induced ( 2 )
Effects of modification on biological processes:
transcription, induced ( 2 )

References 

1

Sacco F, et al. (2016) Deep Proteomics of Breast Cancer Cells Reveals that Metformin Rewires Signaling Networks Away from a Pro-growth State. Cell Syst 2, 159-71
27135362   Curated Info

2

Bastien J, et al. (2000) TFIIH interacts with the retinoic acid receptor gamma and phosphorylates its AF-1-activating domain through cdk7. J Biol Chem 275, 21896-904
10748061   Curated Info

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