Thr700
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Home > Phosphorylation Site Page: > Thr700  -  liprin alpha 1 (mouse)

Site Information
PPGsGRStPRRVPHs   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 31873705

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
'brain, hippocampus' ( 1 ) , HEK293T (epithelial) ( 1 ) , neuron-'brain, hippocampus' ( 1 )

Upstream Regulation
Putative in vivo kinases:
CDK5 (human) ( 1 )
Treatments:
depolarization ( 1 ) , glutamic acid ( 1 ) , seliciclib ( 1 )

Downstream Regulation
Effects of modification on liprin alpha 1:
intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Inhibit interaction with:
PSD-95 (human) ( 1 )

References 

1

Huang H, et al. (2017) Cdk5-dependent phosphorylation of liprinĪ±1 mediates neuronal activity-dependent synapse development. Proc Natl Acad Sci U S A 114, E6992-E7001
28760951   Curated Info

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