Thr124
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.8
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Thr124  -  RFX1 (human)

Site Information
sEAsPGStAsQTGVP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 31871835

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 2 ) , mutation of modification site ( 1 )
Disease tissue studied:
neuroblastoma ( 2 )
Relevant cell line - cell type - tissue:
N1 ( 1 ) , NB10 (neural crest) ( 2 ) , NPC (neural crest) ( 2 )

Upstream Regulation
Putative in vivo kinases:
GSK3B (human) ( 1 )

Downstream Regulation
Effects of modification on biological processes:
transcription, inhibited ( 1 )

References 

1

Kang GM, et al. (2015) Leptin Elongates Hypothalamic Neuronal Cilia via Transcriptional Regulation and Actin Destabilization. J Biol Chem 290, 18146-55
26041775   Curated Info

2

DeNardo BD, et al. (2013) Quantitative phosphoproteomic analysis identifies activation of the RET and IGF-1R/IR signaling pathways in neuroblastoma. PLoS One 8, e82513
24349301   Curated Info