Ser291
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Home > Phosphorylation Site Page: > Ser291  -  TTK (human)

Site Information
CDVktDDsVVPCFMK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 31862439

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
PLK1 (human) ( 1 )
Treatments:
AZD1152 ( 2 ) , ZM447439 ( 2 )

Downstream Regulation
Effects of modification on TTK:
enzymatic activity, induced ( 1 ) , intracellular localization ( 1 )

References 

1

von Schubert C, et al. (2015) Plk1 and Mps1 Cooperatively Regulate the Spindle Assembly Checkpoint in Human Cells. Cell Rep 12, 66-78
26119734   Curated Info

2

Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells. Sci Signal 4, rs5
21712546   Curated Info