Asp324
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Home > Caspase cleavage Site Page: > Asp324  -  RIPK1 (human)

Site Information
RMQsLQLdCVAVPss   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 31845900

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , HeLa (cervical) ( 1 )

Downstream Regulation
Effects of modification on RIPK1:
activity, inhibited ( 1 )
Effects of modification on biological processes:
apoptosis, induced ( 1 )

References 

1

Lin Y, Devin A, Rodriguez Y, Liu ZG (1999) Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev 13, 2514-26
10521396   Curated Info

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