Ser217
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Home > Phosphorylation Site Page: > Ser217  -  axin 1 (human)

Site Information
YTRTGSEsPKVCSDQ   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3174923

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 3 ) , mass spectrometry ( 1 , 2 , 3 ) , mutation of modification site ( 3 ) , western blotting ( 3 )
Disease tissue studied:
lung cancer ( 1 ) , non-small cell lung adenocarcinoma ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative upstream phosphatases:
PPP1CA (human) ( 3 )

Downstream Regulation
Effects of modification on biological processes:
transcription, inhibited ( 3 )
Induce interaction with:
GSK3B (human) ( 3 )

References 

1

Schweppe DK, Rigas JR, Gerber SA (2013) Quantitative phosphoproteomic profiling of human non-small cell lung cancer tumors. J Proteomics 91, 286-96
23911959   Curated Info

2

Dephoure N, et al. (2008) A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A 105, 10762-7
18669648   Curated Info

3

Luo W, et al. (2007) Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex. EMBO J 26, 1511-21
17318175   Curated Info