Tyr750
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Home > Phosphorylation Site Page: > Tyr750  -  MUSK (rat)

Site Information
FGLSRNIySADyyKA   SwissProt
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3146801

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , phospho-antibody ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:
'muscle, skeletal' ( 2 ) , C2.7 (myoblast) ( 2 ) , C2C12 (myoblast) ( 1 )

Upstream Regulation
Treatments:
agrin ( 1 ) , antibody ( 1 ) , AZ23 ( 1 )

Downstream Regulation
Effects of modification on MUSK:
enzymatic activity, induced ( 2 ) , phosphorylation ( 2 )

References 

1

Budayeva HG, et al. (2022) Phosphoproteome Profiling of the Receptor Tyrosine Kinase MuSK Identifies Tyrosine Phosphorylation of Rab GTPases. Mol Cell Proteomics 21, 100221
35227894   Curated Info

2

Herbst R, Burden SJ (2000) The juxtamembrane region of MuSK has a critical role in agrin-mediated signaling. EMBO J 19, 67-77
10619845   Curated Info

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