Lys232
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Home > Tri-methylation Site Page: > Lys232  -  UBF (human)

Site Information
EVKDSLGkQWSQLsD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 31094522

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
neuroblastoma ( 1 )
Relevant cell line - cell type - tissue:
'neuron, striatal' ( 1 ) , HT-22 (neuron) ( 1 ) , SH-SY5Y (neural crest) ( 1 )

Upstream Regulation
Treatments:
siRNA ( 1 )

Downstream Regulation
Effects of modification on UBF:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
chromatin organization, altered ( 1 ) , transcription, inhibited ( 1 )

References 

1

Hwang YJ, et al. (2014) ESET methylates UBF at K232/254 and regulates nucleolar heterochromatin plasticity and rDNA transcription. Nucleic Acids Res 42, 1628-43
24234436   Curated Info

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