Thr251
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Home > Phosphorylation Site Page: > Thr251  -  E2F5 (mouse)

Site Information
SQSSTSVtPQKSTMA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448010

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , electrophoretic mobility shift ( 1 ) , mutation of modification site ( 1 ) , phosphopeptide mapping ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
CDK2 (mouse) ( 1 )
Kinases, in vitro:
CDK2 (mouse) ( 1 )

Downstream Regulation
Effects of modification on E2F5:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
cell cycle regulation ( 1 ) , transcription, induced ( 1 )
Induce interaction with:
p300 (mouse) ( 1 )

References 

1

Morris L, Allen KE, La Thangue NB (2000) Regulation of E2F transcription by cyclin E-Cdk2 kinase mediated through p300/CBP co-activators. Nat Cell Biol 2, 232-9
10783242   Curated Info