Ser827
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Home > Phosphorylation Site Page: > Ser827  -  53BP2 (human)

Site Information
NSDMPAPsPGLDYEP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 30995203

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
bone cancer ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
ERK2 (human) ( 1 )

Downstream Regulation
Effects of modification on 53BP2:
intracellular localization ( 1 )
Effects of modification on biological processes:
apoptosis, induced ( 1 ) , transcription, induced ( 1 )

References 

1

Godin-Heymann N, Wang Y, Slee E, Lu X (2013) Phosphorylation of ASPP2 by RAS/MAPK Pathway Is Critical for Its Full Pro-Apoptotic Function. PLoS One 8, e82022
24312625   Curated Info