Ser463
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus®
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser463  -  MCT1 iso4 (human)

Site Information
EVTKAAEsPDQKDtE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 485800

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 , 4 , 5 , 6 , 7 )
Disease tissue studied:
lung cancer ( 1 , 3 ) , non-small cell lung cancer ( 3 ) , non-small cell lung adenocarcinoma ( 1 )
Relevant cell line - cell type - tissue:
H2009 (pulmonary) ( 3 ) , H2887 (pulmonary) ( 3 ) , H322 (pulmonary) ( 3 ) , HCC366 (pulmonary) ( 3 ) , HCC78 (pulmonary) ( 3 ) , HCC827 (pulmonary) ( 3 ) , HeLa (cervical) ( 2 , 5 , 7 ) , HeLa S3 (cervical) ( 6 ) , HOP62 (pulmonary) ( 3 ) , HUES-9 ('stem, embryonic') ( 4 ) , K562 (erythroid) ( 2 ) , LCLC-103H (pulmonary) ( 3 ) , LOU-NH91 (squamous) ( 3 ) , lung ( 1 ) , NCI-H1395 (pulmonary) ( 3 ) , NCI-H157 (pulmonary) ( 3 ) , NCI-H1666 (pulmonary) ( 3 ) , NCI-H2030 (pulmonary) ( 3 ) , NCI-H460 (pulmonary) ( 3 )

References 

1

Schweppe DK, Rigas JR, Gerber SA (2013) Quantitative phosphoproteomic profiling of human non-small cell lung cancer tumors. J Proteomics 91, 286-96
23911959   Curated Info

2

Zhou H, et al. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome. J Proteome Res 12, 260-71
23186163   Curated Info

3

Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68
22617229   Curated Info

4

Rigbolt KT, et al. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. Sci Signal 4, rs3
21406692   Curated Info

5

Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells. Sci Signal 4, rs5
21712546   Curated Info

6

Daub H, et al. (2008) Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. Mol Cell 31, 438-48
18691976   Curated Info

7

Dephoure N, et al. (2008) A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A 105, 10762-7
18669648   Curated Info

8

Ruse CI, et al. (2008) Motif-specific sampling of phosphoproteomes. J Proteome Res 7, 2140-50
18452278   Curated Info