Tyr4

Site Information
____MDNyADLsDtE SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 3071455

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 2 ) , mass spectrometry ( 1 , 3 ) , mass spectrometry (in vitro) ( 2 ) , mutation of modification site ( 2 )
Relevant cell line - cell type - tissue:	Chang liver (cervical) ( 3 ) , HeLa (cervical) ( 2 ) , Jurkat (T lymphocyte) ( 1 )

Downstream Regulation
Effects of modification on emerin:	molecular association, regulation ( 2 )
Inhibit interaction with:	BAF (human) ( 2 )

References
1	Guo A (2011) CST Curation Set: 11849; Year: 2011; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pTDXEAntibodies Used to Purify Peptides prior to LCMS: Phospho(Ser/Thr) CK2 Substrate (P-S/T3-100) Rabbit mAb Cat#: 8738 Curated Info
2	Tifft KE, Bradbury KA, Wilson KL (2009) Tyrosine phosphorylation of nuclear-membrane protein emerin by Src, Abl and other kinases. J Cell Sci 122, 3780-90 19789182 Curated Info
3	Sui S, et al. (2008) Phosphoproteome analysis of the human Chang liver cells using SCX and a complementary mass spectrometric strategy. Proteomics 8, 2024-34 18491316 Curated Info