Thr573
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Home > Phosphorylation Site Page: > Thr573  -  p90RSK (rat)

Site Information
AENGLLMtPCYTANF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447993

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , mutation of modification site ( 2 ) , phospho-antibody ( 1 , 2 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 2 ) , fibroblast-heart ( 1 ) , myocyte-heart ( 1 )

Upstream Regulation
Regulatory protein:
PKCA (rat) ( 1 ) , PKCD (rat) ( 1 ) , PKCE (rat) ( 1 ) , PRKD1 (rat) ( 1 )
Kinases, in vitro:
ERK1 (human) ( 2 ) , ERK2 (human) ( 2 )
Treatments:
AG1478 ( 1 ) , EGF ( 1 ) , Pasteurella_multocida_toxin ( 1 ) , PD98059 ( 2 ) , phorbol_ester ( 1 , 2 ) , thrombin ( 1 ) , U0126 ( 1 )

Downstream Regulation
Effects of modification on p90RSK:
activity, induced ( 2 )

References 

1

Ozgen N, et al. (2008) Protein kinase D links Gq-coupled receptors to cAMP response element-binding protein (CREB)-Ser133 phosphorylation in the heart. J Biol Chem 283, 17009-19
18378685   Curated Info

2

Dalby KN, et al. (1998) Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK. J Biol Chem 273, 1496-505
9430688   Curated Info