Ser324
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Home > Phosphorylation Site Page: > Ser324  -  TXA2-R (human)

Site Information
RRLQPRLsTRPRsLs   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3061802

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 , 2 ) , phospho-antibody ( 1 , 2 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:
'heart, artery' ( 1 ) , 293 (epithelial) ( 2 ) , HEK293T (epithelial) ( 1 )

Upstream Regulation
Putative in vivo kinases:
PKACA (human) ( 1 )
Kinases, in vitro:
PKCA (human) ( 2 )

Downstream Regulation
Effects of modification on TXA2-R:
activity, inhibited ( 1 ) , molecular association, regulation ( 1 )

References 

1

Santhosh KT, et al. (2014) Thromboxane receptor hyper-responsiveness in hypoxic pulmonary hypertension requires serine 324. Br J Pharmacol 171, 676-87
24490858   Curated Info

2

Yan FX, et al. (2002) Serine 331 is major site of phosphorylation and desensitization induced by protein kinase C in thromboxane receptor alpha. Acta Pharmacol Sin 23, 952-60
12370102   Curated Info