Lys259
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Home > Sumoylation Site Page: > Lys259  -  BMAL1 (human)

Site Information
KCNRPSVkVEDKDFP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3055600

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 2 ) , mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on BMAL1:
intracellular localization ( 2 ) , protein degradation ( 2 )
Effects of modification on biological processes:
transcription, induced ( 2 )

References 

1

Hendriks IA, et al. (2014) Uncovering global SUMOylation signaling networks in a site-specific manner. Nat Struct Mol Biol 21, 927-36
25218447   Curated Info

2

Lee J, et al. (2008) Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex. Mol Cell Biol 28, 6056-65
18644859   Curated Info