Lys333
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Home > Acetylation Site Page: > Lys333  -  SREBP-1 (human)

Site Information
TAHNAIEkRYRSsIN   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 459102

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 2 ) , modification-specific antibody ( 2 ) , mutation of modification site ( 2 ) , western blotting ( 2 )
Disease tissue studied:
liver cancer ( 2 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on SREBP-1:
protein stabilization ( 2 ) , ubiquitination ( 2 )
Effects of modification on biological processes:
transcription, induced ( 2 )

References 

1

Walker AK, et al. (2010) Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. Genes Dev 24, 1403-17
20595232   Curated Info

2

Giandomenico V, Simonsson M, Grönroos E, Ericsson J (2003) Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors. Mol Cell Biol 23, 2587-99
12640139   Curated Info