Lys122
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Home > Acetylation Site Page: > Lys122  -  CREB (human)

Site Information
sRRPsyRkILNDLss   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 459099

In vivo Characterization
Methods used to characterize site in vivo:
immunoassay ( 1 ) , immunoprecipitation ( 1 ) , modification-specific antibody ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
'3T3-L1, differentiated' (adipocyte) ( 1 ) , HEK293T (epithelial) ( 1 ) , MEF (fibroblast) ( 1 )

Upstream Regulation
Treatments:
NKH_477 ( 1 ) , obesity ( 1 ) , selisistat ( 1 ) , TNF ( 1 ) , trichostatin_A ( 1 )

Downstream Regulation
Effects of modification on CREB:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, induced ( 1 )
Induce interaction with:
CBP (human) ( 1 ) , p300 (human) ( 1 )

References 

1

Paz JC, et al. (2014) Combinatorial regulation of a signal-dependent activator by phosphorylation and acetylation. Proc Natl Acad Sci U S A 111, 17116-21
25404345   Curated Info